Complete TCR-a Gene Locus Control Region Activity in T Cells Derived In Vitro from Embryonic Stem Cells
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چکیده
منابع مشابه
Complete TCR-α gene locus control region activity in T cells derived in vitro from embryonic stem cells.
Locus control regions (LCRs) are cis-acting gene regulatory elements with the unique, integration site-independent ability to transfer the characteristics of their locus-of-origin's gene expression pattern to a linked transgene in mice. LCR activities have been discovered in numerous T cell lineage-expressed gene loci. These elements can be adapted to the design of stem cell gene therapy vector...
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